Cosmetic Grade L-Serine(CAS 56-45-1)
Product Name: L-Serine
Abbreviation: L-Ser
Chemical Name: L-2-Amino-3-Hydroxypropanoic Acid
CAS No.: 56-45-1
Grade: Cosmetic Grade (Skin Care Special)
Purity: ≥99.0%
Appearance: White Colorless Crystalline Powder, Odorless, Slightly Sweet Taste
Molecular Weight: 105.09
Molecular Formula: C₃H₇NO₃
MOQ (Minimum Order Quantity): 1KG
Solubility: Easily soluble in water, slightly soluble in ethanol, insoluble in organic solvents, fast dissolution, clear and transparent solution
Specific Rotation: +14.5° ~ +16.5°
pH Value (1% Aqueous Solution): 5.0 - 6.5
Key Characteristics: Natural moisturizing amino acid, excellent skin affinity, mild non-irritating, repair skin barrier, relieve sensitive skin, improve dull complexion, stable formula performance, strong compatibility
Storage Condition: Sealed, dry, cool and dark ventilated environment, avoid high temperature, humid air and direct sunlight, prevent moisture absorption and agglomeration
Shelf Life: 24 Months
Application: Widely used in moisturizing essence, soothing lotion, barrier repair cream, anti-dull skin care products, amino acid skin care formulas and mild functional cosmetics
L-Serine, Cosmetic Grade L-Serine, Skin Moisturizing Agent, Skin Repair Raw Material, Amino Acid Skin Conditioner, Anti-Dullness Cosmetic Additive, Mild Skin Care Ingredient
Cosmetic Grade L-Serine(CAS 56-45-1)
Cosmetic-grade L-Serine is a high-purity natural hydrophilic amino acid extracted and refined by advanced biological fermentation technology, which is an essential nutrient for human skin metabolism.
With rich hydroxyl and amino hydrophilic groups in its molecular structure, it has superior water-locking and moisturizing performance, capable of deeply hydrating the skin, improving dryness, tightness and rough peeling problems.
L-Serine is an important synthetic raw material for skin keratin and natural moisturizing factors, which can effectively promote skin cell metabolism, accelerate barrier repair, enhance skin self-resistance, and relieve redness and sensitivity caused by external stimulation.
Different from ordinary moisturizing ingredients, it has weak acidic pH value close to human skin, ultra-mild properties, no irritation to sensitive muscles, and will not cause skin burden.
It features excellent formula stability, no discoloration or deterioration during long-term storage, and high compatibility with nicotinamide, VC derivatives, hyaluronic acid and other mainstream skin care ingredients. It is a high-quality core raw material for mild moisturizing, barrier repair and brightening skin care products.



Key Benefits
• Deep Hydration & Long-Lasting Moisturizing: Rich dual hydrophilic groups, penetrate deep into the skin, lock moisture efficiently, relieve dry and tight skin, improve rough texture and fine dry lines.
• Barrier Repair & Soothing Stability: Participate in skin natural moisturizing factor synthesis, accelerate damaged barrier repair, enhance skin tolerance, soothe redness and sensitive discomfort.
• Skin-Friendly & Ultra-Mild: Weak acid formula consistent with human skin pH, zero irritation, no sensitization, safe for long-term use on sensitive and fragile skin.
• Brighten & Improve Dullness: Promote skin cell metabolism, accelerate old waste keratin excretion, uniform skin tone, improve yellowish and dull skin, enhance skin translucency.
• Excellent Formula Stability: High-purity refined process, no impurities, no oxidation and discoloration in the formula, stable efficacy and long shelf life of finished products.
• Strong Compatibility & Synergistic Effect: Perfectly compatible with various amino acid ingredients, moisturizers and whitening raw materials, significantly improve the comprehensive skin care effect of the formula.
Applications
• Moisturizing & Hydrating Skin Care Products: Core raw materials for moisturizing toner, lotion, cream and hydrating essence, deeply replenish skin moisture and maintain long-term skin hydration.
• Sensitive Skin Soothing & Repairing Series: Applied in soothing essence, barrier repair cream and after-sun repair products, relieve skin sensitivity and redness, stabilize skin condition.
• Brightening & Anti-Dullness Cosmetics: Added in brightening serum and uniform skin tone products, promote metabolism, fade dullness, and improve skin translucent texture.
• Amino Acid Mild Skin Care Formula: Special raw material for amino acid facial cleanser, mild skin care and infant skin care products, safe and mild with excellent skin affinity.
• Functional Skin Care Auxiliary: Used in anti-aging and moisturizing functional formulas, assist in improving skin elasticity, delay skin aging, and optimize skin texture.
Certificate Of Analysis (COA)
Test Item | Standard Specification | Test Result |
Product Name | L-Serine | Compliant |
CAS No. | 56-45-1 | Compliant |
Appearance | White Crystalline Powder, Odorless | Compliant |
Purity | ≥99.0% | 99.75% |
Specific Rotation | +14.5° ~ +16.5° | +15.6° |
Loss on Drying | ≤0.2% | 0.08% |
Residue on Ignition | ≤0.1% | 0.03% |
Heavy Metal (Pb) | ≤10ppm | Qualified |
Arsenic (As) | ≤2ppm | Qualified |
pH Value (1% Solution) | 5.0 - 6.5 | 5.8 |
Conclusion | Conforms to cosmetic grade quality standard | Qualified |
Frequently Asked Questions (FAQ)
• Q1: What is the MOQ of cosmetic grade L-Serine?
A1: The standard MOQ is 1KG, and sample orders are supported for quality testing.
• Q2: What certification documents can be provided?
A2: Complete COA, MSDS and full set of global customs clearance documents are available.
• Q3: What is the recommended dosage in cosmetic formulas?
A3: Conventional addition ratio is 1.0%-4.0%, with stable moisturizing and repairing effects, no irritation to skin.
• Q4: What are the core skin care effects of L-Serine?
A4: It has multiple effects of deep moisturizing, barrier repair, soothing sensitivity, anti-dullness and metabolism promotion, suitable for all skin types especially sensitive skin.
• Q5: Is it compatible with other skin care ingredients?
A5: Yes, it has excellent compatibility with hyaluronic acid, nicotinamide, amino acid surfactants and other ingredients, with obvious synergistic skin care effect.
• Q6: Do you support stable large-batch supply all year round?
A6: Sufficient factory capacity ensures continuous and stable bulk supply throughout the year.
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